Buses and shared taxis to Tacna, Peru leave regularly all day and take a couple hours. These can be caught from the international bus terminal, which is only about 100 meters from the main bus terminal, across the car park. Buses cost less, but take much longer. From Tacna, buses go regularly to Arequipa, Lima, and Puno. For Cusco, it is necessary to change buses in either Arequipa or Puno.
Buses to Iquique leaves every hour from the main Terminal Rodovario. Tickets are Ch$7000 and the trip takes 5 hours. Also frequent departures to Santiago and two companies operating a daily service to San Pedro de Atacama.
Lauca National Park. Chungará Lake is the main attraction in this wilderness park surrounded by volcanoes and adjacent to the border with Bolivia. Tour operators and touts will try to grab you on the pedestrian streets in the centre, but hiring a car or getting on a bus to Bolivia and getting off in Parinacota on the Chilean side or Lagunas on the Bolivian might work out cheaper.